Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in COPD
نویسندگان
چکیده
Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in COPD Daniel Droemann1, Jan Rupp2, Torsten Goldmann3, Ulrike Uhlig4, Detlev Branscheid5, Ekkehard Vollmer3, Peter Kujath6, Peter Zabel1,7, Klaus Dalhoff7 1Medical Clinic, Research Center Borstel, 23845 Borstel, Germany 2Institute of Medical Microbiology and Hygiene, University of Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany 3Clinical and Experimental Pathology, Research Center Borstel, 23845 Borstel, Germany 4Division of Pulmonary Pharmacology, Research Center Borstel, 23845 Borstel, Germany 5Department for Thoracic Surgery, Krankenhaus Großhansdorf, D-22927 Großhansdorf, Germany 6Department for Thoracic Surgery, University of Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany 7Medical Clinic III, University of Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany
منابع مشابه
Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease.
RATIONALE Chlamydia pneumoniae (Cpn) infection may play a role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Few data are available comparing persistent and acute infection of this pathogen in the human respiratory tract. OBJECTIVES To study Cpn-induced innate immune responses in lung tissue from patients with COPD and control subjects ex vivo and in vitro. METHODS Cp...
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